EFFECT OF D543N AND TGTG DELETION 3’ UTR Nramp1 GENE POLYMORPHISMS AGAINST PULMONARY TUBERCULOSIS AT MELAYU ETHNIC OF SOUTH SUMATERA

-, Yuwono (2010) EFFECT OF D543N AND TGTG DELETION 3’ UTR Nramp1 GENE POLYMORPHISMS AGAINST PULMONARY TUBERCULOSIS AT MELAYU ETHNIC OF SOUTH SUMATERA. In: International Eijkman Institute and NEHCRI Joint Symphosium , 13 - 15 Desember 2010, Hotel Borobudur Jakarta .

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    Abstract

    Pulmonary tuberculosis is still a major health problem with incidence on the world each year 139/100000 population and caused 1,8 million people death.Immunological finding showed that only 10% of population infected by Mycobacterium tuberculosis will get pulmonary tuberculosis, 90% were not get the disease. It is indicated that genetic factors controlling immune responses have major role in the pathogenesis of tuberculosis. Some studies showed 3 kind of genes have major contribution: Mbl gene encoding surface protein in attachment process. Nramp1 gene encoding protein in phogolysosome, responsible for phagocytosis process and Vdr gene encoding protein that regulate cellular immunity.

    Item Type: Conference or Workshop Item (Paper)
    Subjects: R Medicine > R Medicine (General)
    Divisions: Faculty of Medicine > Department of Medicine
    Depositing User: Yon Yuwono
    Date Deposited: 14 Dec 2012 15:58
    Last Modified: 14 Dec 2012 15:58
    URI: http://eprints.unsri.ac.id/id/eprint/1483

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